Skip to main content

Blood sampling for infection is not only based on white blood cells, but this indicator can also be used as a reference. Too high means serious

 Some netizens consulted: I have a cold and fever. It is usually hot at night, but during the day. I went to the hospital for a blood test. They said that the interleukin 6 is high. What is the reason for the high interleukin 6? has no meaning?


Interleukin 6 (IL-6) is a kind of cytokine, belongs to the peptide substance, is a kind of interleukin (a total of 29 kinds), composed of fibroblasts, B lymphocytes, T lymphocytes, macrophages, epithelial cells And a variety of tumor cells are produced and released into the blood. Interleukin 6 plays an important role in maintaining the body's immune response, bone marrow hematopoiesis and inflammation. Under normal circumstances, the content of interleukin 6 in the body is minimal. However, when the body is infected by microorganisms and inflammation occurs, the immune system is activated and interleukin 6 will increase. The increase of interleukin 6 is positively correlated with inflammation. The more severe the inflammation, the higher the interleukin 6 will be. Especially in bacterial infections, the elevated levels of IL-6 are significantly higher than non-bacterial infections.

As early as 2015, "Nosocomial Infection Management Quality Control Indicators" clearly stipulated that the pathogenic detection indicators before antibiotic treatment should include procalcitonin PCT, IL-6 and other indicators. In the early stage of acute infection, IL-6 will rise, the rise of IL-6 is earlier than C-reactive protein (CRP) and procalcitonin (PCT), and it lasts for a long time. After bacterial infection, IL-6 levels increase rapidly and reach a peak within 2 hours. When IL-61 000 pg/ml often indicates poor prognosis.


Is the increase in IL-6 necessarily a bacterial infection?

Not necessarily. Interleukin 6 is involved in the occurrence and development of many diseases, and its level is related to body inflammation, viral infection, autoimmune diseases, malignant tumors, post-transplant rejection, traumatic brain injury, cardiovascular and cerebrovascular diseases, liver cirrhosis, and renal insufficiency. And so on are equally relevant. Therefore, IL-6 may also increase during the acute phase of these diseases.


Autoimmune diseases, such as rheumatoid arthritis, psoriatic arthritis, and compulsive spondylitis, patients will have excess IL-6 in the blood and joints. The new drug tocilizumab is an IL-6 inhibitor. The use of tocilizumab can reduce inflammation, reduce symptoms, reduce joint damage, and improve the quality of life.

The cellular immune function of tumor patients is closely related to the occurrence and development of tumors. When tumor cells proliferate, infiltrate or metastasize, they secrete more endogenous IL-6. Increased levels of IL-6 may indicate the deterioration of patients with malignant tumors, and have certain reference value for evaluating the prognosis of patients.

For people with common upper respiratory tract diseases, if IL-6 is elevated, it may indicate bacterial infection, but it is generally combined with clinical symptoms, blood routine, C-reactive protein, procalcitonin and other comprehensive judgments to guide the use of antibiotics.

Labels:

Comments

Post a Comment

Popular posts from this blog

Jolin Tsai used to have menopause for one year due to excessive weight loss, and now finds the right way to maintain 90 kg for a long time

 The queen of Taiwan, Jolin Tsai, has always been extremely strict with herself, and she often feels that she is not perfect. She used to be of a fleshy body type and was prone to gain weight, so she used extreme weight loss methods. These methods worked quickly in the initial stage, but they were very harmful to her health. I didn't experience it for a year, and later I found a healthy way to lose weight. Not only did I keep my weight at 41kg for a long time, but also became younger and more beautiful. Jolin Tsai’s past weight loss mistakes: Jolin used to go on an extreme diet for weight loss, eating only one meal a day or even nothing. Although he lost weight very quickly at the beginning, once he returned to his normal diet, he would easily rebound, and it would also cause stomach pain, bloating, insomnia, and menopause. In addition, she also tried eating only apples to lose weight, eating only one or two green apples per meal, or eating only one salad, but eating only a single ...
Post a Comment
Read more

Can't sleep? These fruits are natural "sleeping pills"! Let you sleep till dawn!

  Grapes: a sleeping pill for beauty Before falling asleep, a substance called melatonin is secreted in the brain. The night is the most vigorous period of this substance secretion, which indicates that we are about to fall asleep. Studies have confirmed that grapes contain a large amount of melatonin, which can improve the sleep cycle and assist sleep. Studies have also shown that the melatonin content of grapes may be higher after being made into wine, which is more helpful for sleep. Therefore, we can also choose grapes with small particles, high maturity, deep color, and no decay, and use white sugar and yeast to ferment our own wine. Drinking a cup often not only improves sleep, but also plays a role in beauty and anti-aging. Banana: Happy Sleeping Pill Speaking of bananas, everyone is familiar with their laxative effects. The intestines are cleared, toxins are discharged, the body is lighter, and the sleep is naturally improved. And bananas are rich in vitamin B6, which can k...
Post a Comment
Read more

Young people who have experienced the epidemic do not want to trust scientists

  Investigations on past epidemics have found that people who have experienced epidemics between the ages of 18 and 25 have significantly less trust in scientists, especially those with lower levels of scientific education. People who experience epidemics in other age groups or who have a high degree of scientific education are relatively less vulnerable. After the outbreak, related research progress has been exposed by a large number of media, and the public hopes that scientists will develop effective drugs and vaccines as soon as possible. Some people believe that the epidemic will let the public see the importance of public health and even science, but a report released today by the London School of Economics (LSE) pointed out that people who have experienced epidemics between the ages of 18 and 25 have significant trust in scientists. decreased. This report combines the 2018 "Wellcome Global Monitor" (Wellcome Global Monitor) survey of more than 70,000 people in 160 coun...
Post a Comment
Read more